This universe is very similar to the mainstream continuity (Earth-616) with some differences. It also takes place about 19 years after where the current mainstream continuity is currently at in time (August 2008). There is now a new generation of Spider-Man related heroes protecting the world. Some of the new member being the offspring of very notable Spider-Man characters, and some completely new. The world is now also filled with some of the offspring of Spider-Man's well-known enemies.